Angiotensin Receptors Blockers and Cognition in Elderly Home Residents

Document Type : Original Article

Authors

Geriatric Medicine & Gerontology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Abstract

Abstract
Background: Cognitive impairment and hypertension are prevalent in elderly. There is controversial data regarding the impact of angiotensin receptor blockers (ARBs) on cognition.
Aim: To study studied the relation between angiotensin receptor blockers (ARBs) and cognition.
Methods: A case control study was conducted among Cairo’s elderly home residents, aged ≥ 60 years old, between users (n= 10) and non-users (n= 67) of ARBs among hypertensive elderly in long term care centers.
Results: There was no significant difference between users and non-users of ARBs in MMSE, age, systolic blood pressure (SBP), diastolic blood pressure (DBP) (P= 0.76, 0.54, 0.66 and 0.37 consecutively).
Conclusions: No sufficient evidence supports the relation between ARBs and cognition in a sample of hypertensive elderly.

Keywords