Antibiotic Resistance Patterns of Uropathogens in Long Term Care Facilities

Document Type : Original Article

Author

Geriatrics & Gerontology department, Faculty of Medicine, Ain Shams University, Cairo, Egypt.

Abstract

Background: Residence at a Long term care faci l i ty (LTCF) and older age are both recognized as signi ficant risk
factors for harboring mul tidrug resistant Gram-negative bacteria (MDRGNB)
Aim: The objective of this descriptive study is to detect the commonest mul tidrug resistant bacteria and i ts
antibiotic sensi tivi ty in urine of elderly residents at LTCF wi th urinary t ract infection (UTI ) .
Methods: Eighty one LTCF elderly residents wi th UTI. Cul ture and sensi tivi ty was done for urine samples
documenting mul tidrug resistant organisms wi th antibiotic susceptibi l i ty to a range of di f ferent antibiotic groups.
Demographic data was col lected and comorbidi ties were establ ished. Al l samples were processed as per standard
techniques and bacteria identi fied by standard biochemical tests. IBM SPSS statistics (version 24, IBM corp., USA,
2016) was used for data analysis.
Results: The age ranges f rom 60 to 90 years wi th mean 69.86 +/ - 9.68 years Males are 74.1% whi le females are
25.9 %. The predominant resistant detected organism in these samples was Proteus (58.0%) then E col i (19.8 %),
Klebsiela (18.5 %) then Pseudomonas (3.7 %). Proteus is found to be highly statistical ly signi ficant sensi tive to
Cefepime (CPM), Ciprofloxacin (CP), and Imipenam ( IMP) and to be highly statistical ly signi ficant resistant to
Col istin (CT), Gentamycin (GM) , Tobramycin (Tobra. ), Ni trofurantoin (FD) , and Trimethoprim/Sul famethoxazole
(TS). E Col i is found to be highly statistical ly signi ficant sensi tive to Col istin (CT), Trimethoprim/ Sul famethoxazole
(TS), Gentamycin (GM), Tobramycin(Tobra. ) and Ni trofurantoin (FD) and resistant to Cefepime (CPM) . Further
studies are recommended on larger numbers of elderly patients to confi rm or not confi rm signi ficant findings in this
study, t ry to explain these findings, and make use of i t in cl inical practice.
Conclusion: Proteus is the commonest mul ti resistant uropathogen in those under 70 years whi le psuedomonas is
the most prevalent one in elderly between71 -90 years of age

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