The Profile of Multi Drug Resistant Bacterial Infections in Long Term Care Facility

Author

Geriatrics and Gerontology Department, Faculty of Medicine- Ain Shams University

Abstract

Aim: To detect the commonest mul tidrug resistant bacteria and i ts antibiotic sensi tivi ty in elderly residents at LTCF
Methods: 126 LTCF elderly residents and documented mul ti drug resista nt organisms in thei r samples. Cul ture and
sensi tivi ty was done for col lected samples documenting mul tidrug resistant organisms wi th i ts antibiotic susceptibi l i ty
to a range of di fferent antibiotic groups. Demographic data was col lected and comorbidi ties were establ ished. Al l
samples were processed as per standard techniques and bacteria identi fied by standard biochemical tests. IBM SPSS
statistics (version 24, IBM corp., USA, 2016) was used for data analysis.
Results: The age range f rom 60 to 98 years wi t h mean 70.5794 +/- SD 10.17years. Males are 79 (~62.27%) , whi le
females are 47(~37.37%), The predominant resistant detected organism in these samples is Proteus (49.2 %), then
Klebsiela (22.2 %) , then E Col i (11.1%), then Pseudomonas (9.5%), then MRSA (4.8%) and lastly, Mix of [Klebsiela +
Pseudomonas ] ~ (3.2%) . Proteus is found to be highly statistical ly signi ficant sensi tive to Meronam (MEM) , Imipenam
(IMP), Ciprofloxacin (CP) and highly statistical ly signi ficant resistant to Cefuroxime (CRM) , Ceftazidime (CAZ) ,
Gentamycin (GM), Col istin (CT) , Trimethoprim/Sul famethoxazole (TS), Ni t rofurantoin (FD) , Tobramycin (Tobra) whi le
Klebsiel la is highly statistical ly signi ficant sensi tive to Ceftazidime (CAZ) , Col istin (CT) and highly statistical ly
signi ficant resistant to Imipenam ( IMP) and E Col i is found to be highly statistical ly signi ficant sensi tive to Gentamycin
(GM) and Ni t rofurantoin (FD) whi le Pseudomonas is highly statistical ly signi f icant sensi tive to Tobramycin and highly
statistical ly signi ficant resistant to CD,MEM, Minocycl in (MN) ,Vancomycin .MRSA is found to be highly statistical ly
signi ficant sensi tive to to Trimethoprim/Sul famethoxazole (TS), Cl indamycin (CD) , Minocycl in (MN) , and Vancomycin
whi le the mix of Klebsiel la + Pseudomonas is highly statistical ly signi ficant sensi tive to Tobramycin.
Conclusions: Gram negative bacteria are the most common mul tidrug resistant bacteria at long term care faci l i ty
mostly Proteus, the best antibiotics to use for proteus infections was Minocycl in (MN) then Meronam (MEM) then
Imipenam (IMP).

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